Endocrine Abstracts

Introduction: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, with an incidence in the literature of 0.5 to 2 cases per million population per year. The most important prognostic factors are stage of cancer at the time of diagnosis and success of the first surgery. However, advanced age, tumor size, functionality, high Ki-67 index (>10%), necrosis, and high mitotic activity are among poor prognostic factors.Patients and method: Fifteen...

Introduction: Generally, symptoms of celiac disease is not accompanied when present together with autoimmune endocrine diseases. In this study, we aimed to investigate the prevalence of silent celiac disease in the APS and autoimmune monoglandular disorders by measuring tissue transglutaminase antibodies (ttgAb).Methods: A total of 103 patients with monaglandular or polyglandular autoimmune endocrine disorders and 32 control subjects were enrolled in the...

Introduction: Spondyloepiphyseal dysplasia congenita (SEDC) is a rare congenital disease of skeletal system,which is characterized by short stature, shortage of trunk and mostly affect vertebral column and epiphysis of long bones. In this case report, we aimed to represent a patient complaining of short stature and referred to our hospital,who was detected to have an early onset osteoporosis accompanied by proximal femoral aplasia; in the light of literature.<p class="abst...

Introduction: Vitamin D Deficiency has been widely regarded as contributing to autoimmune disease, but low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause like from malabsorbtion due to celiac disease, gastrointestinal disorders related to diabetes or thyroid disease, corticosteroid therapy complications etc\..In this study, we aimed to investigate vitamin d levels in autoimmune endocrine disorders and relationship with silent celiac...

One of the main problems encountered with increased levels of serum PTH is decrease in bone mineral density in the long term. Secondary hyperparathyroidism due to vitamin D deficiency leads to mineralization disorders of the bones, low bone mineral density, osteoporosis and ultimately an increased risk of bone fracture in adults. In this study, we aimed to determine the reasons of secondary hyperparathyroidism for bone mineral density.One hundred and thi...

In this study, we aimed to investigate the causes of elevated PTH levels in postmenopausal women without the use of drugs that may affect of PTH levels and without concomitant diseases.A total of 156 postmenopausal women, aged ≥ 50 years, had no menstruation for at least 2 years and had no disease known to affect calcium metabolism were considered. Education, occupation, average duration of exposure to sunlight per day in summer and winter, consump...

Background: Hemangiopericytoma (HPC) is a malignant vasculary tumor originate from pericytes around the capillary and venules. İntracranial hemangiopericytomas usually arise from meninges, rarely they locate periventricular, suprasellar or sellar. Because of the malignancy potential, the differential diagnosis is important. A rare case of sellar HPC mimicking non-functional pituitary adenoma will be presented.Case report: A 45 years old woman has a...

Objective: The prevalence of overweight and obesity has been increasing for several decades. Few studies have recently showed functional and morphological changes of the thyroid gland in relation to obesity. The aim of this study was to correlate thyroid nodule size with body mass index (BMI), waist-hip ratio (WHR) and thyroid stimulating hormone (TSH) levels.Methods: A total of 119 patients diagnosed with euthyroidic nodular goiter were included in this...

Introduction: Thyroid papillary carcinomas originate from thyroid follicular epithelia and are the most frequent thyroid differentiated carcinomas. Medullary thyroid carcinomas originate from thyroid parafollicular C cells and %25 are a component of Multiple Endocrine Neoplasia (MEN) syndromes. Co-incidence of the two condition on the same patient is so rare.Case: 78 years old female patient who has had simple goiter for 10 years, was investigated about ...

Introduction: Differentiated thyroid carcinomas (DTC) are originated from thyroid follicular epithelial cells and comprises %90 of all thyroid carcinomas. Researches indicate that sorafenib is more efficacious than other chemotherapeutic agents on metastatic iodide refractory DTCs.Material and methods: In our center, between 2013 and 2015, sorafenib was applied to six patients who had iodide refractory metastatic DTC. Five of the patients were female. Th...